Raffaele Coppini conducted a cohort study of patients with hypertrophic cardiomyopathy (HCM), the outcome indicated that, among patients with HCM, most patients have a mutation in TNNT2, and these patients are more likely to suffer from arrhythmias and HCM in the future [51]. The gene discussed is TNNT2; the disease is cardiac arrhythmia.