STX1B and epilepsy with myoclonic atonic seizures: Tang et al. (2020) showed that pathogenic genetic variants in SYNGAP1, NEXMIF, SLC6A1, KCNA2, SCN2A, STX1B, KCNB1, MECP2, ASH1L, CHD4, and SMARCA2 are the cause of seizures in 14% of MAE individuals. Our data suggest that PIGT is a new candidate gene for MAE.