From another perspective, correlation analysis in our study showed that the identified key genes CCL8, CCL18, CCL19, CXCL16, and VCAM1 were related to lipid metabolism biomarkers, which were closely related to the occurrence of CAVD from a biochemical point of view. This evidence concerns the gene CXCL16 and congenital bilateral aplasia of vas deferens from CFTR mutation.