The results of the AUC comparisons were as follows: LODS versus SAPS II (Z = 5.122, P < 0.0001), LODS versus SIRS (Z = 7.075, P < 0.0001), LODS versus SOFA (Z = 5.796, P < 0.0001), SAPS II versus SIRS (Z = 10.127, P < 0.0001), SAPS II versus SOFA (Z = 9.417, P < 0.0001), SIRS versus SOFA (Z = 3.280, P = 0.0010). This evidence concerns the gene SKAP2 and systemic inflammatory response syndrome.