Nonetheless, this should result in therapeutic levels of LUM at the tumor site because LUM is substantially more cytotoxic to NSCLC cells compared to other common chemotherapeutics encapsulated into thermosensitive liposome formulations, such as doxorubicin78 and CDDP, that have IC50 values in the high nanomolar and low micromolar range. This evidence concerns the gene LUM and neoplasm.