UALCAN was also used to analyze the expression of SKA genes in HCC and normal tissues, and the results showed that the expression of SKA1 (P = 1.62e−12), SKA2 (P = 1.62e−12), and SKA3 (P < 1e−12) increased significantly in HCC tissues (Fig. 2a). The gene discussed is SKA3; the disease is hepatocellular carcinoma.