Although Met-1 TripZ-200c cells showed increased tumorigenic properties when compared to Met-1 TripZ-EV cells at baseline (-Dox), Dox treatment in Met-1 TripZ-200c cells alone significantly decreased each one of these phenotypes, suggesting that miR-200c restoration might also affect mammary tumor progression in vivo. The gene discussed is GZMM; the disease is breast cancer.