In breast cancer cells, IGF2BP3 has a direct correlation with E-cadherin, vimentin, and Slug (P < 0.05) and further promotes invasion and migration by prompting the EMT83 and reducing cell apoptosis by activating the Hedgehog signalling pathway CD44/CD44+Fbs/IGF2 [59, 106]. This evidence concerns the gene CD44 and breast cancer.