As different BIRC5 isoforms showed distinct links with chemotherapy responses and the function of each isoforms in GC is not fully understood [25], we analyzed the cellular phenotypes upon BIRC5-202 or -203 overexpression in GC by transfection of pcDNA-BIRC5-202 or -203 in HGC-27 cells (Fig. 7b). This evidence concerns the gene BIRC5 and gastric cancer.