In this study, firstly, we have demonstrated that AATK/miR-1250 was frequently methylated in NHL cell lines and NHL primary samples, but unmethylated in healthy normal controls, hence a tumor-specific pattern of methylation in NHL, similar to tumor-specific pattern of methylation of other tumor suppressor miRNAs, such as miR-155-3p [18], miR-124-1 [29], and miR-203 [30] in NHL cells. Here, AATK is linked to neoplasm.