High levels of pro-inflammatory markers, such as IL-6 and IL-8 have been observed in ALS patients (Blasco et al., 2017) and causative genes of ALS including MATR3, and PFN1 and TDP‐43 are enriched and associated with inflammation (Umoh et al., 2018). Here, TARDBP is linked to amyotrophic lateral sclerosis.