High levels of pro-inflammatory markers, such as IL-6 and IL-8 have been observed in ALS patients (Blasco et al., 2017) and causative genes of ALS including MATR3, and PFN1 and TDP‐43 are enriched and associated with inflammation (Umoh et al., 2018). The gene discussed is MATR3; the disease is amyotrophic lateral sclerosis.