Second, the ROC analysis results for admission MMP-8 in predicting 90 days mortality in critically ill acute respiratory failure patients resembled the results in the present study where day 5 MMP-8 predicted death within 90 days with an AUC of 0.61, cut-off 149 ng/mL, sensitivity and specificity of 65% and 54% [15]. The gene discussed is MMP8; the disease is acute respiratory failure.