To assess the potential cellular interactions in vivo, we counted the number of S100A8hi neutrophils in close proximity to CD48+ and CD48− MKs, respectively, and found that the CD48+ MKs exhibited a much higher potential to interact and/or recruit S100A8hi neutrophils than CD48− MKs under both homeostasis and infection conditions (Figure 6H; Figure S6F,G, Supporting Information). This evidence concerns the gene CD48 and infection.