Under the similar hyperglycaemia condition in STZ‐induced diabetic rat, Wnt3a/β‐catenin pathway was found to be inhibited in cardiomyocytes,43 but swimming exercise was proved to alleviate insulin resistance through inhibiting the overactivated Wnt3a/β‐catenin pathway in skeletal muscles.44 The gene discussed is WNT3A; the disease is Insulin resistance.