An in vivo study shows that the mRNA and protein levels of Wnt2, β‐catenin and Wnt target genes are all increased progressively in myocardial tissues from rat following streptozotocin (STZ)‐induced diabetes, which is accompanied by the cardiac dysfunction and progressive cardiomyocyte apoptosis, suggesting that the activation of Wnt2/β‐catenin pathway may facilitate the development of diabetic cardiomyopathy.33 Here, WNT2 is linked to diabetic cardiomyopathy.