Among all the patients with CRC, TP53, APC, and KRAS co‐mutations were observed in 10 patients (13.3%), and co‐alterations of TP53/APC, TP53/KRAS, and APC/KRAS were present in 27 (36.0%), 20 (26.7%) and 19 patients (25.3%), respectively. The gene discussed is KRAS; the disease is colorectal carcinoma.