For example, Chen et al. fabricated poly(lactic-co-glycolic acid) (PLGA)-ICG NPs to generate mild heat under NIR light irradiation and found that the mild heat could trigger increased infiltration and accumulation of the chondroitin sulfate proteoglycan-4- (CSPG4-) specific CAR T cells in tumor tissues [242]. Here, CSPG4 is linked to neoplasm.