Results showed that copy numbers of CEP63 (p<0.01) and FOSL2 (p<0.01) were significantly gained in 40 BC urine sediment samples compared with 42 control urine sediment samples (Supplementary Figure 4), which was consistent with the real-time PCR results of tumor samples and 123 urine sediment samples. The gene discussed is CEP63; the disease is breast cancer.