EPHX2 and chronic kidney disease: The grouped genotypes of rs11780592 EPHX2 polymorphism differed significantly also, among stages of diabetic CKD -G1/G2 as mild CKD, G3a/G3b as moderate CKD, G4 as severe CKD, and G4 as ESRD (p = 0.02), Supplementary Table 3.