As the aim of this work was to understand how melanoma TME affects the infiltration of CD8+ T cells, we excluded CD8+ T cell specific markers (CD8A, CD8B, GZMK and NKG7), as well as genes expressed in most CD8+ T cells (more than 50%) but in less than 10% of the remaining cells in the melanoma TME. The gene discussed is CD8A; the disease is melanoma.