PDCD1 and neoplasm: Although the anti-PD-L1 activity of Y111 may block the PD1/PD-L1 interaction and act as a checkpoint inhibitor, our data showed that the PDL1-antibody alone had little effect on the killing ability of the Vγ2Vδ2 T cells against PDL1-positive tumor cells (Figure 5). We noticed that only four pair dots might not provide meaningful correlations, but we indeed found a negative trend between the Y111-induced killing ability (EC50 values) and the PD-L1 positive percentages (Supplementary Table 1).