For example, Wang et al. developed a personalized cancer vaccine (termed PVAX) by integrating JQ1 (an inhibitor of PD-L1 expression) and indocyanine green (ICG, a photosensitizer) co-loaded autologous tumor cells into a hydrogel matrix composed of tumor-penetrable peptides (Wang et al., 2018). Here, CD274 is linked to neoplasm.