In the lung metastatic mouse model, the BC exosomal miR-183-5p could transfer to macrophages to promote the secretion of pro-inflammatory cytokines interleukin-1b (IL-1β), IL-6, and tumor necrosis factor-α, via repressing phosphatase 2 catalytic subunit alpha (PPP2CA)60. Here, IL6 is linked to breast cancer.