The highly differential genes between the two groups showed that C–C motif chemokine ligand 3 (CCL3) and X-C motif chemokine ligand 1 (XCL1) were significantly elevated in endometriosis while cytotoxic molecules including GNLY, GZMB and GZMH were significantly down-regulated (Fig. 6d). The gene discussed is GZMB; the disease is endometriosis.