DLX6 and hepatocellular carcinoma: Next, HCC-exo delivering oe-DLX6-AS1 or sh-DLX6-AS1 were co-cultured with macrophages and the results disclosed that DLX6-AS1 level was increased or decreased in macrophages in a time-dependent manner (Fig. 4e, 5b), confirming that HCC-exo could deliver DLX6-AS1 to macrophages.