Because our prior results suggested that KSRP acts as a component of the functional oncogenic KITENIN axis that modulates CRC cell invasion (Fig. 1e), we investigated whether Dvl affects the oncogenic context of the KITENIN complex through binding KSRP and, if so, whether DKC1125 can modulate these interactions. Here, VANGL1 is linked to colorectal carcinoma.