The total number of CRC identified was 71 (50% path_MLH1, 36% path_MSH2, 6% path_MSH6, 8% path_PMS2) as well as 20 endometrial, nine breast, five ovarian, four urothelial (75% path_MSH2) and two small bowel cancers. This evidence concerns the gene MLH1 and colorectal carcinoma.