MMP11 and cancer: Pictilisib and AZ960 reduced the growth of cancer cell lines with high MMP-11 expression [pictilisib: r = -0.291, p = 0.04 (Pearson’s correlation) and 0.026 (Student’s t-test); AZ960: r = -0.314, p = 0.043 and 0.009] (Fig 5A and 5B).