ECM1 and neoplasm: Differential expression between the mesenchymal-like and bulk tumor cells revealed lower expression of EPCAM, while higher expression of CD44 and mesenchymal markers such as VIM, COL1A1, MMP7, ECM1, and SPARC (Figure 6H), the latter previously identified to peak at intermediate EMT levels and predicted by RNAvelocity to earmark a subpopulation of plastic cells transitioning in between states (Figure 5D–G).