MAPT and Alzheimer disease: Our cohorts were selected in such a way, that the results of the four AD CSF biomarkers (Aβ1-42, Aβ42/40 ratio, Tau, and pTau181) were considered the major categorization criterion, with the patterns of the CSF biomarkers interpreted according to the Erlangen Score algorithm (Lewczuk et al. 2009, 2015).