MAPT and Alzheimer disease: This approach, taken together with moderate correlation between αSyn and Tau and/or pTau181, might explain why αSyn sensitivity and specificity, in the setting AD versus controls, resulted in our study in somehow larger ROC AUC and better diagnostic accuracy than those metrics reported by (Korff et al. 2013), and comparable to those reported by (Majbour et al. 2017).