MAPT and Alzheimer disease: Increased αSyn concentrations in the AD subjects, along with moderate correlation between αSyn and Tau and/or pTau181 in the current study reconfirm the data and the conclusions reported by many investigators, that the increased CSF αSyn in AD seems to rather reflect unspecific neurodegeneration and not specific processes characteristic for AD (Oeckl et al. 2016; Korff et al. 2013; Slaets et al. 2014; Majbour et al. 2017).