CD27 and tuberculosis: Whereas this effect was initially hypothesized to be solely a feature of M. tuberculosis-specific T cells,8 we recently showed that the expression of CD27 was generally impaired in tuberculosis patients and that this effect was not restricted to M. tuberculosis-specific T cells.2 Similarly, we found lower IL-7 receptor (CD127) expression in T cells from tuberculosis patients than in T cells from controls.5 Aberrant phenotypes in tuberculosis pathology are not restricted to T cells but also affect innate immune cells such as monocytes.