Multinominal regression Cox's analysis showed that the risk of death in CRC patients was 2.3 times higher in patients with IMP3 positive expression than in patients with IMP3 negative expression (p = 0.027), also there was 10.4 times higher mortality rate in subjects with vascular invasion compared to patients without vascular invasion (p < 0.001). Here, IMP3 is linked to colorectal carcinoma.