The median CMV IgM antibody was 0.07 (IQR 0.04–0.18; normal range 0–12) AU/mL and CMV IgG antibody was 874.11 (IQR 341.11–1518.74; normal range 0–14) AU/mL in 59 COVID-19 patients. The gene discussed is CD40LG; the disease is COVID-19.