ERBB2 and ductal breast carcinoma in situ: In a comparison of 53 cases of high-grade DCIS, enriched for large lesions, to 65 cases of low-grade DCIS, immune infiltrates were correlated with high-risk DCIS features (high Van Nuys Prognostic Index, palpability, high-grade, comedonecrosis, high Ki67, HR-negative, and HER2-positive).