Our independent analysis of primary ER+PIK3CA-mutant breast cancers, which exhibit high INPP4B expression, identified these and additional upregulated Wnt genes (LEF1, MYCN, FZD7, SFRP2, TCF7L1, CTNNB1, FZD4, and SFRP1). This evidence concerns the gene TCF7L1 and breast carcinoma.