SOX2 and teratoma: These hiPSCs stained positively for pluripotency markers OCT4, SOX2, NANOG, SSEA4 and TRA-1–60 (Fig. S2a), formed the three germ layers in a teratoma assay (Fig. S2b), were karyotypically normal (Fig. S2c), and were sequenced to confirm their HNF1A c.376 C > G (H126D) genotype (Fig. S2d).