The COX2/PGE2 axis was found to be positively associated with choline-deficient/l-amino acid-deficient diet (CDAA)-, TAA-, and bile duct ligation (BDL)-induced rat liver fibrosis [10, 11] and liver cirrhosis in rats, mice, and patients [9, 12]. The gene discussed is PTGER2; the disease is Hepatic fibrosis.