PTGS2 and Hepatic fibrosis: To evaluate the correlation between the COX2/PGE2 axis and hepatic fibrosis, the transcriptional levels of COX2, Ptges, Ptger1-4, Abcc4, and Slco2a1 in mice liver were measured using RT-qPCR (Fig. 1a), and the translational levels of COX2, mPGES-1, and EP1-4 in mice liver were detected by western blotting (Fig. 1b) in 8-week Sj-infected and uninfected mice groups.