Autoimmune hyperthyroidism, also known as Graves’ disease (GD), is associated with TSH-receptor antibodies (TRAb) [39], whereas autoimmune hypothyroidism, also known as Hashimotos’ thyroiditis, is associated with thyroid peroxidase (TPO) and thyroglobulin (Tg) antibodies [38]. This evidence concerns the gene TG and Graves disease.