On the one hand, more than half of complex (17/27 cases, 63.0 %) and mixed (7/10 cases, 70 %) tumours according their histologic subtype had luminal immunophenotypes (A or B); on the other hand, more than half of simple tumours (13/21 cases, 61.9 %) were classified as HER2-overexpression or TN inmmunophenotypes (Table 3). The gene discussed is ERBB2; the disease is neoplasm.