The patients in the anemia-ABI had significantly a worse ECOG-PS (P = 0.039), higher initial PSA (P = 0.001), EOD (P = 0.002), ALP (P = 0.010), and LDH (P = 0.017) than those in the non-anemia-ABI group (Table 1). Here, KLK3 is linked to anemia.