PLOD1 and central precocious puberty: Basal E2 and peak LH levels in the girls with organic CPP and early-stage puberty (Tanner stage 2 and 3) were similar to those in the girls with idiopathic CPP and advanced-stage puberty (Tanner stage 4) (basal E2: 62.4 ± 19.8 pg/mL vs. 64.6 ± 21.2 pg/mL, P = 0.844; peak LH: 16.8 ± 3.2 IU/L vs. 16.6 ± 5.8 IU/L, P = 0.642).