A more complex culture system has been designed by co‐culturing of gastric tumour organoids from mouse model with cytotoxic T lymphocytes (CTLs) and bone marrow‐derived DCs pulsed by conditioned media (tumour antigen) collected from cancer organoids, it turned out that in this system, tumour cell apoptosis is increased in gastric tumour organoids by activated CTLs in the presence of PD‐L1 neutralizing antibody.51 Here, CD274 is linked to gastric neoplasm.