For thyroid gland cancer prediction, thyroglobulin antibody in serum or plasma by immunoassay (2.69%), thyroglobulin in serum or plasma (0.58%), T4 (thyroxine) (0.62%), and gene telomerase reverse transcriptase (TERT) (SHAP value 0.59%) were found to be the major contributors. The gene discussed is TERT; the disease is thyroid cancer.