Subsequently, the level of miR-542-3p in CRC cells transfected with si-TUG1 or pcDNA-TUG1 was measured, and the data confirmed that TUG1 silencing markedly upregulated miR-542-3p, while upregulation of TUG1 significantly downregulated miR-542-3p. Here, TUG1 is linked to colorectal carcinoma.