PNP and gout: Vitamin B12 (permease protein and substrate binding protein), nucleoside permease, glycine cleavage system transcriptional repressor, several xanthine dehydrogenase iron-sulfur-binding subunits, xanthine and nucleoside phosphorylases, methionine transaminase, oxidoreductases, transferases, hydrolases were much higher in the fecal microbiome of tophaceous gout patients compared to healthy controls.