IL6 and fatty liver disease: Additionally, pathologic examination further confirmed the therapeutic potency of A. muciniphila in ameliorating all the phenotypes of MAFLD in mice, namely hepatocyte injury and ballooning (indicated by H&E staining), hepatic steatosis (indicated by oil red O (ORO) staining), and inflammation (indicated by IL-6 and CD68 examination) (Figure 1g).