In addition, the expression of CREB1 was associated with the pathologic stage and T of HCC patient specimens (P = 0.043 and 0.046, respectively).Furthermore, the expression of CREB1 was related to OS (P = 0.021), PFI (P = 0.011), DFI (P = 0.017), and DSS (P = 0.0064) in HCC patients, which was positively correlated with MeCP2 expression (P < 0.001, r = 0.47) (Fig.␣S6). The gene discussed is MECP2; the disease is hepatocellular carcinoma.