NFKB1 and intervertebral disk degenerative disorder: Guo et al139 reported that the circular RNA, FAM169A, acts as a competitive endogenous RNA and, by targeting miR‐583 and BTRC signals as well as through the NF‐κB signalling pathway, it regulates the imbalance between NP cell ECM anabolism and catabolism, thus affecting the IDD process.