Furthermore, a screen in zebrafish for genes that regulate motile cilia showed that morpholino oligo-mediated depletion of spag6 resulted in pronephric cysts, but not other characteristics of PCD-associated defects in zebrafish, such as body curvature and hydrocephalus (Austin-Tse et al., 2013). The gene discussed is SPAG6; the disease is Hydrocephalus.