The results of WB and RT-qPCR assays suggested that the levels of OSX, OCN and COL1 were downregulated in the OM + pcDNA-circ_0062582 + miR-145 mimic group as comparison to the OM + pcDNA-circ_0062582 + miR-NC group (Figure 2j). The gene discussed is SP7; the disease is ocular melanoma.