In earlier studies of glutamate-induced cytotoxicity, various cell lines and primary cortical cells have been utilized (Kritis et al., 2015), and the glutamate transporter GLT1 and GLAST have been shown to link neurological disorders with oxidative and glutamate stress (Sheldon and Robinson; Olivares-Bañuelos et al., 2019). The gene discussed is SLC1A3; the disease is nervous system disorder.